A colony of Swiss mice has not been heard from or seen in many years. Basil, the mouse detective, and his friend, Dr. Dawson, solve the mystery about the disappearance of that colony.
Anatole the mouse returns from vacation to find that he is sorely needed to help solve the mystery of the Great Cheese Robbery, which has closed his good friend's cheese factory.
Anatole, a music-loving mouse, plays the miniature piano in the museum, saving a concert for the orphans of Paris by removing a broken string of pearls from the piano.