Charles and Lizzie Peterson love puppies. They want a puppy of their own more than just about anything. They know dogs are a lot of work. But their Mom still doesn't think their family is ready for a puppy. Then, Goldie arrives. She is a sweet golden retriever who needs a home.
Lizzie Peterson, who takes care of animals whenever she can, offers to lend a hand when an energetic Dalmatian is left on their porch, but when the puppy destroys Lizzie's Halloween costume, she's not sure if she can convince an owner to adopt him.
Charles and Lizzie go to the dog show with their Aunt Amanda and agrees to take care of Ziggy, a dachshund puppy whose owner has too many dogs to take care of, until he can be placed in a permanent home with a new family, but Ziggy runs away and Charles is determined to recover the lost puppy.
Charles and his new friend, David, try to help a stray puppy they find while camping by taking him to the veterinarian and searching for a home for him.
Charles and Lizzie Peterson are happy to help the puppies who lost their home in a flood, especially after meeting a basset mix named Lucy, but when items in their house begin to disappear, they learn that Lucy has a unique habit.
Charles takes in Sweetie, a tiny poodle puppy, but Buddy gets jealous every time Sweetie comes too close to Charles and Lizzie, who try to find a new home for Sweetie before Buddy's feelings get hurt.
