While spending a month on an island off the coast of Washington helping in her Uncle Sanjay's veterinary clinic, eleven-year-old Poppy Ray soon questions her decision to follow in her uncle's footsteps.
With the help of her veterinarian grandmother and the other volunteers at the Wild at Heart Animal Clinic, eleven-year-old Maggie rescues sick puppies from an illegal puppy mill.
Zoe, having accustomed herself to life with her veterinarian grandmother and the flock of wild parrots that live in the backyard, is confused about her feelings when her mother arrives to take her to a new home in Los Angeles.
After treating an injured greyhound at her grandmother's veterinary clinic, thirteen-year-old Maggie learns about the abuse of greyhounds in the dog-racing industry and vows to put a stop to it.
Seeing Jane's dog, Yum-Yum, help cheer up children in a cancer ward makes Zoe think about having her puppy, Sneakers, trained to do therapy, too, especially when Yum-Yum becomes very ill.
While staying at her parent's vacation house in the Lake District, Mandy and James find a Labrador on the lawn, but he has no identification and no way of finding the owner.
During the school holiday performance Honey the hamster escapes from her cage and was last seen scurrying out into the snow under a holly bush; and now Mandy and James must find her before she freezes to death.