Although Cork the muskrat is short and likes to find things and Fuzz the possum is tall and likes to keep things, the pair remain best friends even after Fuzz finds Cork's lost stone and decides to keep it.
After Andy hosts a barn sale to raise money for a case for Granny Webb's binoculars, he realizes that they accidentally were sold, so with Dolores's help they try to track down the missing binoculars.
While looking for his lost magnifying glass in the park, young Detective Jeffrey Bones and his grandfather discover that Curly the detective dog is missing, too, and start tracking down clues.
When Adele walks her little brother Simon home from school he loses one more thing at every stop: his drawing of a cat at the grocer's shop, his books at the park, his crayons at the art museum, and more.
C.J., who aspires to be as great a jazz musician as his uncle, searches for Uncle Click's hat in preparation for an important photograph and inadvertently gathers some of the greatest musicians of 1950s Harlem to join in on the picture.
After Detective Dinosaur and Officer Pterodactyl find a missing baby wearing pink diapers and a home for Cadet Kitty, they lose and rediscover each other.